Timor-Tritsch L E, Lerner J P, Monteagudo A, Santos R
Department of Obstetrics and Gynecology, Sloane Hospital for Women, Columbia-Presbyterian Medical Center, New York, NY 10032.
Am J Obstet Gynecol. 1993 Mar;168(3 Pt 1):909-13. doi: 10.1016/s0002-9378(12)90843-1.
The aim of the study was to test the hypothesis that a combination of a previously devised morphologic scoring system and color flow-directed Doppler measurements would afford better discrimination between benign and malignant ovarian masses.
The scoring system and color flow-directed Doppler measurements for 115 masses were prospectively analyzed and correlated with histopathologic surgical findings.
In 21 masses (18 patients) no flow was obtained. Seventy-eight masses in 70 patients were benign, and 16 masses in 12 patients were malignant. The mean total score for the benign masses was 6.7 and for the malignant masses 11.7. The resistance index was 0.64 for the benign lesions and 0.39 for the malignant masses (range 0.2 to 0.98). The mean pulsatility index of the benign masses was 1.17 and 0.52 for the malignancies (range 0.2 to 2.6). There were no malignancies in the group with no flow obtained. The sensitivity and specificity of score alone was 94% and 87%, respectively, with a 60% positive predictive value. By means of resistance index or pulsatility index the sensitivity was 94%, the specificity 99%, and the positive predictive value 94%.
These results suggest that Doppler flow measurements alone and in conjunction with a scoring system help differentiate benign from malignant masses.
本研究旨在验证以下假设，即先前设计的形态学评分系统与彩色血流导向多普勒测量相结合，能更好地区分卵巢良性和恶性肿块。
对115个肿块的评分系统和彩色血流导向多普勒测量进行前瞻性分析，并与组织病理学手术结果相关联。
21个肿块（18例患者）未检测到血流。70例患者中的78个肿块为良性，12例患者中的16个肿块为恶性。良性肿块的平均总评分为6.7分，恶性肿块为11.7分。良性病变的阻力指数为0.64，恶性肿块为0.39（范围为0.2至0.98）。良性肿块的平均搏动指数为1.17，恶性肿块为0.52（范围为0.2至2.6）。未检测到血流的组中无恶性肿块。仅评分的敏感性和特异性分别为94%和87%，阳性预测值为60%。通过阻力指数或搏动指数，敏感性为94%，特异性为99%，阳性预测值为94%。
这些结果表明，单独的多普勒血流测量以及与评分系统相结合有助于区分良性和恶性肿块。
