Shields J A, Shields C L, Eagle R C, De Potter P, Oliver G L
Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107.
Br J Ophthalmol. 1993 Mar;77(3):187-9. doi: 10.1136/bjo.77.3.187.
A 76-year-old man with compressive optic neuropathy secondary to a retrobulbar mass was managed by orbitotomy and removal of the mass. The lesion proved histopathologically to be an unusual orbital melanoma with massive central necrosis. There was no histopathological evidence of congenital melanocytosis. Dermatological and systemic evaluation before and after orbital surgery revealed no evidence of primary melanoma elsewhere. The patient developed hepatic metastasis 2 years after excision of the orbital tumour. It appears that the melanoma was a primary orbital tumour and not a metastatic melanoma from an occult primary lesion.
一名76岁男性因球后肿块继发压迫性视神经病变，接受了眼眶切开术并切除肿块。组织病理学检查证实该病变为罕见的眼眶黑色素瘤，伴有大片中央坏死。没有先天性黑素细胞增多症的组织病理学证据。眼眶手术前后的皮肤科和全身评估均未发现其他部位存在原发性黑色素瘤的证据。患者在眼眶肿瘤切除术后2年出现肝转移。看来该黑色素瘤是原发性眼眶肿瘤，而非隐匿性原发灶转移而来的黑色素瘤。
