Lysosomal storage diseases in livestock.

Lysosomal storage diseases may be inherited or acquired. The former are usually inherited as autosomal traits, and heterozygotes may be identified by having enzyme activity levels approximately midway between normal and diseased values. Founder effect, enhanced by widespread acceptance of artificial breeding technologies, has been important in the spread of these genetic diseases in cattle. Acquired storage diseases of importance to livestock most frequently are plant intoxications.