Guerra L, Vincenzi C, Peluso A M, Tosti A
Department of Dermatology, University of Bologna, Italy.
Contact Dermatitis. 1993 Feb;28(2):101-3. doi: 10.1111/j.1600-0536.1993.tb03351.x.
Acrylate-based products are widely utilized in the industrialized world and in the domestic environment. The aim of this study was to evaluate the prevalence and sources of occupational contact sensitization to acrylates in a selected population. Between January 1987 and April 1992, 82 patients suspected of occupational acrylic sensitization were patch tested with the GIRDCA standard series and an extensive acrylate series. Over this 5-year period, we detected sensitization to acrylates in 13.4% of cases. Dental materials and anaerobic sealants were the most important sources of acrylate sensitization. Among acrylic monomers, ethylene glycol dimethacrylate was the most frequent contact sensitizer in our study. Acrylate additives were also important sources of contact dermatitis in our patients. Although the clinical picture of airborne contact dermatitis due to acrylates has rarely been reported in the literature, it was commonly observed in our patients.
丙烯酸酯类产品在工业化国家和家庭环境中都有广泛应用。本研究的目的是评估特定人群中职业性接触性致敏丙烯酸酯的患病率及来源。1987年1月至1992年4月期间，对82名疑似职业性丙烯酸酯致敏患者进行了GIRDCA标准系列和广泛丙烯酸酯系列的斑贴试验。在这5年期间，我们检测到13.4%的病例对丙烯酸酯致敏。牙科材料和厌氧密封剂是丙烯酸酯致敏的最重要来源。在丙烯酸单体中，乙二醇二甲基丙烯酸酯是我们研究中最常见的接触致敏剂。丙烯酸酯添加剂也是我们患者接触性皮炎的重要来源。尽管文献中很少报道因丙烯酸酯引起的空气传播性接触性皮炎的临床表现，但在我们的患者中很常见。
