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久坐不动者、运动者及心力衰竭患者的血管传导率与有氧能力

Vascular conductance and aerobic power in sedentary and active subjects and heart failure patients.

作者信息

Reading J L, Goodman J M, Plyley M J, Floras J S, Liu P P, McLaughlin P R, Shephard R J

机构信息

School of Physical and Health Education, University of Toronto, Ontario, Canada.

出版信息

J Appl Physiol (1985). 1993 Feb;74(2):567-73. doi: 10.1152/jappl.1993.74.2.567.

DOI:10.1152/jappl.1993.74.2.567
PMID:8458771
Abstract

The relationship between peak aerobic power and a strain-gauge determination of local skeletal muscle vascular conductance 10-13 s after calf exercise to fatigue was examined in 21 middle-aged adults (age 38.1 +/- 2.5 yr): seven physically active men (A), seven sedentary men (S), and six men and one woman with compensated idiopathic heart failure (HF). The three subgroups were chosen as differing widely in peak O2 intake [48.2 +/- 1.2, 32.9 +/- 1.6, and 16.1 +/- 1.3 (SE) ml.kg-1 x min-1, respectively]. Calf vascular conductance showed a gradation with aerobic power: 64.8 +/- 3.8, 40.7 +/- 4.3, and 30.7 +/- 6.1 (SE) ml/min local flow per 10 liters of tissue per unit of blood pressure. There was a strong positive correlation between O2 intake and vascular conductance for the overall group (VO2 = 0.614 G + 3.5; r = 0.75, P < 0.001) and for the 14 normal subjects (VO2 = 0.377 G + 20.6; r = 0.74, P < 0.002). The mean conductance was smaller in HF (P < 0.001), with no significant slope in relation to O2 intake. There was no relationship between the resting cardiac ejection fraction [74.4 +/- 4.1% (SE) for A, 74.3 +/- 4.2% for S, and 25.8 +/- 5.2% for HF] and either peak aerobic power or calf vascular conductance. We conclude that peak aerobic power is strongly associated with local vascular conductance during peripherally limited exercise involving the calf muscles of one leg and that vascular conductance is particularly low in subjects with compensated idiopathic heart failure.

摘要

在21名中年成年人(年龄38.1±2.5岁)中,研究了小腿运动至疲劳后10 - 13秒时的峰值有氧功率与局部骨骼肌血管传导性的应变计测定值之间的关系:7名体育活动男性(A组)、7名久坐男性(S组)以及6名男性和1名患有代偿性特发性心力衰竭(HF)的女性。选择这三个亚组是因为它们的峰值摄氧量差异很大[分别为48.2±1.2、32.9±1.6和16.1±1.3(SE)ml·kg⁻¹·min⁻¹]。小腿血管传导性随有氧功率呈现梯度变化:每10升组织每单位血压下的局部血流量分别为64.8±3.8、40.7±4.3和30.7±6.1(SE)ml/min。总体组(VO₂ = 0.614G +

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