Amso N N, Shaw R W
Academic Department of Obstetrics and Gynaecology, Royal Free Hospital School of Medicine, London, UK.
Hum Reprod. 1993 Jan;8(1):168-74. doi: 10.1093/oxfordjournals.humrep.a137865.
Several treatments for infertility have been promoted with only little supporting objective data demonstrating their therapeutic value. The choice of an assisted reproductive technique depends on a balance between numerous factors. Seldom is the choice absolute as in patients with tubal block. There is conflicting evidence on the efficacy of simpler methods such as ovarian stimulation with or without artificial insemination and the available data suggest that the more invasive methods such as gamete intra-Fallopian transfer or in-vitro fertilization are more effective in the treatment of couples with unexplained infertility. Equally, there is no conclusive evidence that pregnancy rates with any of the invasive techniques are superior to any others. However, a higher implantation rate following tubal embryo transfers is observed in many studies. This review presents a critical assessment of the effectiveness of assisted reproductive techniques.
有几种治疗不孕症的方法得到了推广，但仅有很少的客观数据支持来证明其治疗价值。辅助生殖技术的选择取决于众多因素之间的平衡。像输卵管堵塞的患者那样选择绝对单一的治疗方法的情况很少见。关于诸如单纯的卵巢刺激加或不加人工授精这类较简单方法的疗效，存在相互矛盾的证据，现有数据表明，诸如配子输卵管内移植或体外受精这类侵入性更强的方法，在治疗不明原因不孕症的夫妇时更有效。同样，也没有确凿证据表明任何一种侵入性技术的妊娠率优于其他技术。然而，许多研究观察到输卵管胚胎移植后的着床率较高。本综述对辅助生殖技术的有效性进行了批判性评估。
