Zimmerman B R, Molnar G D
Mayo Clin Proc. 1977 Apr;52(4):233-7.
Because no complete long-term follow-up of visual status after pituitary ablation has been reported, records were reviewed on all 40 patients undergoing sectioning of the pituitary stalk for diabetic retinopathy at the Mayo Clinic from 1961 through 1968. One patient died and another was blind immediately postoperatively. One patient was lost to follow-up after 125 months. Twenty-seven patients have died after a follow-up interval of 7 to 120 months (mean, 63 months). The last available evaluation of these patients indicated stable or improved visual acuity in 20 patients. Eleven patients remain alive. Seven of these have stable or improved visual acuity and retinopathy. We conclude that although late post-operative mortality is high, in carefully selected patients with florid retinopathy but no fibrosis, pituitary ablation is an effective method for maintaining visual acuity.
由于此前尚无关于垂体切除术后视力状况的完整长期随访报告，我们回顾了1961年至1968年间在梅奥诊所因糖尿病性视网膜病变接受垂体柄切断术的所有40例患者的记录。1例患者术后死亡，另1例术后即刻失明。1例患者在125个月后失访。27例患者在7至120个月（平均63个月）的随访期后死亡。对这些患者的最后一次有效评估表明，20例患者的视力稳定或改善。11例患者仍存活。其中7例患者的视力和视网膜病变稳定或改善。我们得出结论，尽管术后晚期死亡率很高，但对于精心挑选的患有严重视网膜病变但无纤维化的患者，垂体切除是维持视力的有效方法。
