Elshot S R, el Gamal M I, Tielen K H, van Gelder B M
Department of Cardiology, Catharina Hospital, Eindhoven, The Netherlands.
Int J Cardiol. 1993 Mar;38(3):303-8. doi: 10.1016/0167-5273(93)90249-g.
The incidence of atrioventricular (AV) block and chronic atrial flutter/fibrillation was determined in 41 patients, mean age 62.2 years (22 to 88 years) who received atrial pacemakers before October 1980. The mean follow-up period was 12.3 years, range 11-14.4 years. Twenty-five patients suffered from bradycardia-tachycardia syndrome, 13 symptomatic bradycardia, and 3 bradycardia related ventricular tachycardia. At follow-up: 18 patients (44%) had permanent I-AV block; 11 patients had II-AV block, 9 patients (22%) transient Wenckebach block and 2 patients (5%) transient Mobitz block, all asymptomatic. The cumulative incidence of III-AV block was 1 (2.5%). Chronic atrial flutter/fibrillation occurred in 6 patients (15%), 5 were not pacemaker-dependent; 1 received a ventricular pacemaker. Seventeen patients died after a mean of 7 years (0.6-12.2 years). Cumulative survival rate of 58% for 14.4 years, did not differ from a matched cohort of the normal population. There were no pacemaker related deaths. We conclude that long-term atrial pacing was safe and effective. The incidence of III-AV block and chronic atrial flutter/fibrillation was low.
对41例于1980年10月前接受心房起搏器植入的患者(平均年龄62.2岁,22至88岁)进行了房室(AV)阻滞及慢性心房扑动/颤动发病率的测定。平均随访期为12.3年,范围为11至14.4年。25例患者患有心动过缓 - 心动过速综合征,13例有症状性心动过缓,3例有与心动过缓相关的室性心动过速。随访时:18例患者(44%)发生永久性I度房室阻滞;11例患者发生II度房室阻滞,9例患者(22%)出现短暂性文氏阻滞,2例患者(5%)出现短暂性莫氏阻滞,均无症状。III度房室阻滞的累积发病率为1例(2.5%)。6例患者(15%)发生慢性心房扑动/颤动,5例不依赖起搏器;1例接受了心室起搏器。17例患者在平均7年(0.6至12.2年)后死亡。14.4年的累积生存率为58%,与正常人群的匹配队列无差异。无起搏器相关死亡。我们得出结论,长期心房起搏是安全有效的。III度房室阻滞和慢性心房扑动/颤动的发病率较低。