Prasher D, Cohen M
Medical Research Council, Human Movement and Balance Unit, National Hospital for Neurology and Neurosurgery, London, UK.
Scand Audiol. 1993;22(1):11-8. doi: 10.3109/01050399309046013.
This study examines the acoustic reflex threshold criteria, derived from a large group of patients with cochlear hearing loss proposed by Cohen & Prasher (1992), in order to evaluate their effectiveness in differentiating between cochlear and retro-cochlear lesions. This criterion was tested on 63 patients with surgically confirmed cerebello-pontine angle (CPA) lesions. The false results obtained with this and other criteria were compared. The best balance between the false positive and negative results in the cochlear and retrocochlear group is provided by the criterion of any two adjacent test frequencies (proposed in the companion paper) having an upper limit of 105 dB for hearing below 60 dB and 110 dB for hearing over 60 dB. This study has also singled out the interaural difference criterion as the best diagnostic indicator with the lowest false results with only 1 false negative from 63 CPA cases and 3 false positive cases from 61 cochlear lesions with hearing thresholds over 55 dB.
本研究考察了科恩和普拉舍尔(1992年)提出的、源自大量耳蜗性听力损失患者的听觉反射阈值标准,以评估其在区分耳蜗性病变和蜗后病变方面的有效性。该标准在63例经手术确诊为桥小脑角(CPA)病变的患者身上进行了测试。将该标准及其他标准得出的错误结果进行了比较。对于耳蜗组和蜗后组,在假阳性和假阴性结果之间实现最佳平衡的标准是:任意两个相邻测试频率(在配套论文中提出),听力低于60 dB时上限为105 dB,听力高于60 dB时上限为110 dB。本研究还选出耳间差异标准作为最佳诊断指标,其错误结果最少,在63例CPA病例中只有1例假阴性,在61例听力阈值超过55 dB的耳蜗病变中有3例假阳性。