Libeer J C, Tertoolen J F
Department of Clinical Biology, Institute of Hygiene and Epidemiology, Brussels, Belgium.
Scand J Clin Lab Invest Suppl. 1993;212:39-42.
A common survey for immunoassays was organized for Belgian and Dutch laboratories. We compared the different statistical approaches used in the two schemes; both approaches lead to comparable results. Differences in overall consensus values and overall precision are related to a different selection of kits in the two countries. When analyzing results from users of representative kits in both countries, we found a very good correlation in accuracy but detected also some significant differences in precision for some samples for cortisol and theophylline determinations. For some observed differences there is actually no acceptable explanation.
为比利时和荷兰的实验室组织了一项常见的免疫分析调查。我们比较了两种方案中使用的不同统计方法;两种方法得出的结果相当。总体共识值和总体精密度的差异与两国试剂盒的不同选择有关。在分析两国代表性试剂盒用户的结果时,我们发现准确度方面有很好的相关性,但在皮质醇和茶碱测定的某些样本的精密度方面也发现了一些显著差异。对于一些观察到的差异,实际上没有可接受的解释。