Georgopoulos A P, Taira M, Lukashin A
American Legion, Minneapolis, MN.
Science. 1993 Apr 2;260(5104):47-52. doi: 10.1126/science.8465199.
A major challenge of current neuroscience is to elucidate the brain mechanisms that underlie cognitive function. There is no doubt that cognitive processing in the brain engages large populations of cells. This article explores the logic of investigating these problems by combining psychological studies in human subjects and neurophysiological studies of neuronal populations in the motor cortex of behaving monkeys. The results obtained show that time-varying psychological processes can be visualized in the time-varying activity of neuronal populations. Moreover, the functional interactions between cells in the motor cortex are very similar to those observed in a massively interconnected artificial network performing the same computation.
当前神经科学面临的一个主要挑战是阐明认知功能背后的大脑机制。毫无疑问，大脑中的认知处理涉及大量细胞。本文探讨了通过结合对人类受试者的心理学研究和对行为猴子运动皮层中神经元群体的神经生理学研究来研究这些问题的逻辑。所获得的结果表明，时变的心理过程可以在神经元群体的时变活动中可视化。此外，运动皮层中细胞之间的功能相互作用与在执行相同计算的大规模互连人工网络中观察到的相互作用非常相似。
