Dalbak L G, Theodorsen L, Aune M W, Sandberg S
Sentrallaboratoriet, Det Norske Radiumhospital, Oslo.
Tidsskr Nor Laegeforen. 1993 Feb 28;113(6):709-12.
A fully automated reticulocyte counter, Sysmex R-1000 has been evaluated at three Norwegian hospitals. The instrument measures fluorescence-labelled RNA in the reticulocytes by flow cytometry. It also generates information on reticulocyte maturity. Instrument precision was superior to that achieved with the routine visual counting method. Samples preserved at room temperature remain stable for one day, whereas samples preserved at 5 degrees C remain stable for four days. An increasing number of reticulocytes is often the first sign of marrow regeneration after bone marrow transplantation or treatment of leukaemia with cytostatica. In patients with chronic renal failure who are receiving erythropoietin, the increase in reticulocytes is seen within days, and precedes the increase in haemoglobin by 2-3 weeks.
Sysmex R - 1000全自动网织红细胞计数仪已在挪威的三家医院进行了评估。该仪器通过流式细胞术测量网织红细胞中荧光标记的RNA。它还能生成有关网织红细胞成熟度的信息。仪器的精密度优于常规目视计数法。室温保存的样本可稳定一天，而5摄氏度保存的样本可稳定四天。网织红细胞数量增加通常是骨髓移植或用细胞抑制剂治疗白血病后骨髓再生的首个迹象。在接受促红细胞生成素治疗的慢性肾衰竭患者中，数天内即可见到网织红细胞增加，且比血红蛋白增加提前2 - 3周。
