Kanamaru H, Shirahase T, Moroi S, Taniguchi T, Kuo J Y, Okuno H, Kihara Y, Arai Y
Department of Urology, Public Toyooka Hospital.
Hinyokika Kiyo. 1993 Feb;39(2):127-30.
We assessed the clinical significance of multiple mucosal biopsies in new cases of superficial papillary bladder tumor. Biopsy findings were abnormal (5 dysplasia, 5 transitional carcinoma) in 10 of the 71 cases examined. Abnormalities were observed exclusively at G2 or G3, and more frequently at pT1 than pTa. Cases with multiple tumors showed significantly more abnormalities than cases with a solitary tumor. Recurrence rates were not significantly different between the cases with abnormal biopsy findings and those with normal findings. However, the invasive tumor developed more frequently in the former. Mucosal biopsies seemed to be more useful in cases with multiple tumors than in those with a solitary tumor.
我们评估了多次黏膜活检在浅表乳头状膀胱肿瘤新发病例中的临床意义。在71例接受检查的病例中，有10例活检结果异常（5例发育异常，5例移行细胞癌）。异常仅在G2或G3期观察到，且在pT1期比pTa期更常见。多发肿瘤病例的异常情况明显多于单发肿瘤病例。活检结果异常的病例与结果正常的病例之间的复发率无显著差异。然而，前者发生浸润性肿瘤的频率更高。黏膜活检在多发肿瘤病例中似乎比在单发肿瘤病例中更有用。
