McClellan W
Division of Nephrology, Emory School of Medicine, Atlanta, GA.
Am J Kidney Dis. 1993 Apr;21(4 Suppl 1):25-30. doi: 10.1016/0272-6386(93)70072-7.
The end-stage renal disease (ESRD) networks and the United States Renal Data System recently have described the epidemiology of ESRD and broadened our appreciation of the impact of ESRD in the United States. This surveillance system also can be used to study the occurrence and control of ESRD. Among the epidemiologic study designs available to conduct research on the etiology of renal failure, case-control studies are uniquely suited for this purpose. The case of hypertensive ESRD illustrates this concept; risk factors for hypertensive ESRD, as a hypothetical exposure in case-control studies, are briefly described. Case-control studies are an efficient and readily used means to study causes of renal failure.