McSwiney M M, O'Farrell D, Joshi G P, McCarroll S M
Department of Anaesthesia, Cappagh Hospital, Dublin.
Can J Anaesth. 1993 Mar;40(3):222-6. doi: 10.1007/BF03037034.
This study was designed to evaluate the effect of transfusion guidelines on perioperative blood usage with a view to identifying a protocol for transfusion therapy in our hospital. Eighty consecutive patients with normal haemoglobin concentrations presenting for total hip arthroplasty were studied. The maximum allowable blood loss (MABL) was calculated for each patient using the formula of Kallos et al. Blood loss up to this value was replaced with Haemaccel. When the MABL was reached, a haematocrit (Hct) was performed and blood was given if the Hct was less than 30 in men and 27 in women. Otherwise replacement was with Haemaccel. All postoperative complications, duration of hospital stay, and physiotherapy compliance assessments were recorded. A discharge Hct > 36% was the criterion for overtransfusion. The results were compared with findings from a retrospective group before the introduction of these guidelines. Analysis of the data demonstrated a reduction in the frequency of transfusion (97% vs 32% P < 0.05), the volume transfused (2.7 vs 1.3 units P < 0.05), and the incidence of overtransfusion (45% vs 5% P < 0.05) between the two groups of patients. There was no difference between the groups in complication rate, duration of hospital stay or physiotherapy scoring. We conclude that the introduction of guidelines for transfusion in total hip arthroplasty patients has produced a marked reduction in blood usage in our hospital without detrimental effect.
本研究旨在评估输血指南对围手术期用血的影响,以期确定我院输血治疗的方案。对80例血红蛋白浓度正常且拟行全髋关节置换术的连续患者进行了研究。使用Kallos等人的公式为每位患者计算最大允许失血量(MABL)。失血量达到该值时,用贺斯(Haemaccel)补充。当达到MABL时,检测血细胞比容(Hct),若男性Hct小于30、女性Hct小于27,则输血,否则用贺斯补充。记录所有术后并发症、住院时间及物理治疗依从性评估情况。出院时Hct>36%作为输血过量的标准。将结果与引入这些指南之前的回顾性队列研究结果进行比较。数据分析表明,两组患者之间输血频率(97%对32%,P<0.05)、输血量(2.7单位对1.3单位,P<0.05)及输血过量发生率(45%对5%,P<0.05)均有所降低。两组患者在并发症发生率、住院时间或物理治疗评分方面无差异。我们得出结论,全髋关节置换术患者输血指南的引入使我院用血显著减少,且无不良影响。