Thomson J D, Callaghan J J, Savory C G, Stanton R P, Pierce R N
J Bone Joint Surg Am. 1987 Mar;69(3):320-4.
We retrospectively analyzed a program of prior deposit and storage of autologous blood that was used for patients who underwent elective orthopaedic procedures over a period of thirty-six months at the Walter Reed Army Medical Center. Of a total of 211 patients who underwent total joint replacement or spinal fusion during this period and who had sufficient records to be included in the study, a total of 159 patients enrolled in the program. The fifty-two patients who did not enroll in the study, twelve of whom were rejected because of medical problems, served as a control group. Since the preoperative hematocrit values for patients in the group that received autologous blood were similar to those for the control group, multiple preoperative phlebotomies in these patients, who had received supplemental iron, did not seem to have any deleterious effects. One hundred and thirteen (71 per cent) of the 159 patients who were enrolled in the program received only autologous blood. The remaining forty-six patients required homologous blood also, but 64 per cent of their transfusion needs were provided by autologous blood. The only reactions to the transfusions in the study were in four patients who received homologous blood. We think that a program of prior deposit and storage of autologous blood should be an option for patients who are to undergo elective orthopaedic surgery. Such a program is well tolerated by the patients and easily managed by the staff, and it was not difficult to implement at our tertiary referral hospital.
我们回顾性分析了一项自体血预先储存计划,该计划应用于在沃尔特·里德陆军医疗中心接受择期骨科手术的患者,为期36个月。在此期间,共有211例接受全关节置换或脊柱融合手术且有足够记录可纳入研究的患者,其中159例患者加入了该计划。未加入该研究的52例患者作为对照组,其中12例因医疗问题被排除。由于接受自体血患者组的术前血细胞比容值与对照组相似,这些接受过铁补充剂的患者术前多次采血似乎并未产生任何有害影响。加入该计划的159例患者中,113例(71%)仅接受了自体血。其余46例患者也需要异体血,但他们64%的输血需求由自体血提供。该研究中仅4例接受异体血的患者出现了输血反应。我们认为,自体血预先储存计划应作为择期骨科手术患者的一个选择。该计划患者耐受性良好,工作人员易于管理,并且在我们的三级转诊医院实施并不困难。