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[有毒污染物与生育障碍。溶剂和杀虫剂]

[Toxic pollutants and fertility disorders. Solvents and pesticides].

作者信息

Gerhard I, Eckrich W, Runnebaum B

机构信息

Abteilung für Gynäkologische Endokrinologie und Fertilitätsstörungen, Universitäts-Frauenklinik Heidelberg.

出版信息

Geburtshilfe Frauenheilkd. 1993 Mar;53(3):147-60. doi: 10.1055/s-2007-1023656.

DOI:10.1055/s-2007-1023656
PMID:8467981
Abstract

It is demonstrated by means of extensive reference studies, as well as own results, that organic solvents and pesticides can be accountable for intoxications and various complications during pregnancy (e.g. abortion, stillbirth, intrauterine growth retardation). An initial stimulation of the adrenal cortex (hyperandrogenaemia) can result in partial insufficiency of the adrenal cortex with symptoms like alopecia and feeling of sickness. Consequences can be hypo- and hyperthyroidism. The immunological system is affected (e.g. abortion, susceptibility to infections). Neurovegetative and neuropsychological concomitant symptoms are numerous. Toxic contaminants affect men at different levels of the semen producing organs (e.g. oligospermia, azoospermia). Indications regarding diagnosis of toxic substances related illnesses as well as therapeutic and prophylactic potentialities are presented.

摘要

通过广泛的参考文献研究以及自身研究结果表明,有机溶剂和农药可能导致孕期中毒及各种并发症(如流产、死产、胎儿宫内发育迟缓)。肾上腺皮质的初始刺激(高雄激素血症)可导致肾上腺皮质部分功能不全,出现脱发和恶心等症状。其后果可能是甲状腺功能减退和亢进。免疫系统会受到影响(如流产、易感染)。伴有许多神经植物性和神经心理症状。有毒污染物会在精液生成器官的不同层面影响男性(如少精子症、无精子症)。本文还介绍了与有毒物质相关疾病的诊断指征以及治疗和预防潜力。

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引用本文的文献

1
[Environment and reproduction].[环境与生殖]
Arch Gynecol Obstet. 1995;257(1-4):239-46. doi: 10.1007/BF02264829.