Uno H, Murai N, Fukunishi K
Advanced Research Laboratory, Hitachi Ltd., Saitama, Japan.
Neurosci Lett. 1993 Feb 19;150(2):179-82. doi: 10.1016/0304-3940(93)90530-x.
We examined spatio-temporal characteristics of the tonotopic representation in the auditory cortex of the anesthetized guinea pig with a multichannel optical method using voltage-sensitive dye. The response latencies increased, and the response field in the cortex became small when the stimulus intensity levels were decreased. Low frequencies were represented rostrally and high frequencies caudally. The two fields responding to different frequencies at higher intensity levels gradually overlapped as time after stimulus onset increased, though these response field did not overlap at the beginning of the response. These findings indicate that tonotopic representation varies dynamically with time after stimulus onset.
我们使用电压敏感染料，通过多通道光学方法研究了麻醉豚鼠听觉皮层中声调定位表征的时空特征。当刺激强度水平降低时，反应潜伏期延长，皮层中的反应区域变小。低频在嘴侧代表，高频在尾侧代表。在较高强度水平下，对不同频率作出反应的两个区域随着刺激开始后的时间增加而逐渐重叠，尽管这些反应区域在反应开始时并不重叠。这些发现表明，声调定位表征在刺激开始后的时间里动态变化。
