Fukunishi K, Murai N
Advanced Research Laboratory, Hitachi Ltd., Saitama, Japan.
Biol Cybern. 1995;72(6):463-73. doi: 10.1007/BF00199889.
The neural network structure of a guinea-pig's primary auditory cortex is estimated by applying pattern-time-series analysis to the auditory evoked responses. Spatiotemporal patterns in click-evoked responses, observed by optical recording with voltage-sensitive dye, are analyzed by time series analysis using a multivariable autoregressive (MAR) model. Oscillatory neural activities with a distribution of about 10 approximately 40 Hz in the click-induced evoked responses are found in the cortical response field. The cortical regions where the distributed neural oscillations are generated are identified by pattern-time-series analysis. In addition, two types of cortico-cortical connections, unilateral and bilateral connections between the cortical points, are speculated to be the causes of oscillatory neural activity transfer. It can be said that the so-called synchronized neural oscillation, in the sense of coherency or correlation between the two evoked responses at the oscillatory frequency, does not necessarily represent real cortico-cortical neural connections at the evoked response points.
通过对听觉诱发反应应用模式时间序列分析，估计豚鼠初级听觉皮层的神经网络结构。利用电压敏感染料进行光学记录观察到的点击诱发反应中的时空模式，使用多变量自回归（MAR）模型通过时间序列分析进行分析。在皮层反应场中发现了在点击诱发反应中具有约10至40 Hz分布的振荡神经活动。通过模式时间序列分析确定产生分布式神经振荡的皮层区域。此外，推测皮层点之间的两种类型的皮质-皮质连接，即单侧和双侧连接，是振荡神经活动转移的原因。可以说，从振荡频率下两个诱发反应之间的相干性或相关性意义上讲，所谓的同步神经振荡不一定代表诱发反应点处真正的皮质-皮质神经连接。
