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念珠菌性尿路感染:对其诊断与管理的全面综述

Candidal urinary tract infections: a comprehensive review of their diagnosis and management.

作者信息

Gubbins P O, Piscitelli S C, Danziger L H

机构信息

University of Arkansas for Medical Sciences, Little Rock.

出版信息

Pharmacotherapy. 1993 Mar-Apr;13(2):110-27.

PMID:8469618
Abstract

Despite its prevalence, the significance of candiduria remains uncertain. The pathogenesis of candidal urinary tract infections has been relatively well characterized and many risk factors have been identified. The disorders lack consistent diagnostic criteria, however, such as the presence of pyuria or a colony count above which is predicative of presence, location, or severity of infection. Treatment is unclear due to lack of data defining the natural progression of the disease. Although often recommended, it may not always be possible to remove risk factors. Amphotericin B, fluconazole, 5-flucytosine, and other antifungal agents are important agents for managing candidal urinary tract infections.

摘要

尽管念珠菌尿症很常见,但其重要性仍不明确。念珠菌性尿路感染的发病机制已得到较好的描述,并且已确定了许多危险因素。然而,这些病症缺乏一致的诊断标准,例如脓尿的存在或高于该数值的菌落计数可预测感染的存在、位置或严重程度。由于缺乏定义该疾病自然进展的数据,治疗方法尚不清楚。虽然通常建议去除危险因素,但并非总是可行。两性霉素B、氟康唑、5-氟胞嘧啶和其他抗真菌药物是治疗念珠菌性尿路感染的重要药物。

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