Jonte F, Rayón C, Medina J, García Gala J, García Jalón A, Fanjul E, Morante C, Fresno M, Coma A, Arribas M
Servicio de Hematología, Hospital Central de Asturias, Oviedo.
Sangre (Barc). 1993 Feb;38(1):1-4.
To evaluate the incidence of CML in Asturias during the period 1972-1986, studying the variations in relation to age, sex and geographical zone.
Information relating to the date of diagnosis, name, age, sex and home address of the 108 cases (65 men and 43 women) diagnosed CML during the period 1972-1986 according to conventional criteria was collected from the hospital records of the region. For the calculations, SADEI demographic data were taken as a reference, comparing the incidence between sexes and geographical zones by means of the CHI2.
A rate of incidence of 0.64/100,000 inhabitants/year was obtained, this being 0.8 in men and 0.5 in women (p < 0.05). The rate of incidence increased progressively with age until the 45-59 age group when it was maximum. There were no differences between the three main centres of population Gijón (0.53), Oviedo (0.55) and Avilés (0.69) nor the latter with the rest of the zones in Asturias; nor was three either any difference between coastal towns (0.56) and those of the interior (0.71) (p = NS).
Limited incidence of CML in Asturias without significant differences in its geographical distribution within the region. The incidence, which was higher among males, increased progressively with age until reaching maximum importance in the 45-59 age group.
评估1972 - 1986年期间阿斯图里亚斯地区慢性粒细胞白血病（CML）的发病率，研究其在年龄、性别和地理区域方面的变化。
从该地区医院记录中收集了1972 - 1986年期间根据传统标准诊断为CML的108例患者（65名男性和43名女性）的诊断日期、姓名、年龄、性别和家庭住址等信息。计算时，以西班牙人口与住房普查（SADEI）的人口数据为参考，通过卡方检验比较性别和地理区域之间的发病率。
得出的发病率为0.64/100,000居民/年，男性为0.8，女性为0.5（p < 0.05）。发病率随年龄逐渐升高，在45 - 59岁年龄组达到最高。吉洪（0.53）、奥维耶多（0.55）和阿维莱斯（0.69）这三个主要人口中心之间以及它们与阿斯图里亚斯其他地区之间没有差异；沿海城镇（0.56）和内陆城镇（0.71）之间也没有差异（p = 无显著性差异）。
阿斯图里亚斯地区CML发病率有限，在该地区内其地理分布无显著差异。发病率男性较高，随年龄逐渐升高，在45 - 59岁年龄组达到最高。
