Pienta K J, Esper P S
Meyer L. Prentis Comprehensive Cancer Center of Metropolitan Detroit, Michigan.
Ann Intern Med. 1993 May 15;118(10):793-803. doi: 10.7326/0003-4819-118-10-199305150-00007.
To review the current state of knowledge regarding risk factors for prostate cancer.
Analysis of the literature through the use of MEDLINE as well as identification of papers through review of article bibliographies and the authors' personal files. Current data were also extracted from the Surveillance, Epidemiology, and End Results Program (SEER) database.
A review of risk factors for the development of prostate cancer. Emphasis was placed on identifying larger, controlled studies.
The clinical incidence of prostate cancer is increasing. Risk factors for prostate cancer appear to include age, race, positive family history, vasectomy, and dietary fat intake.
It appears that prostate cancer results from an interplay between endogenous hormones and environmental influences that include, most prominently, dietary fat.
回顾目前关于前列腺癌危险因素的知识现状。
通过使用MEDLINE对文献进行分析，并通过查阅文章参考文献和作者个人档案来识别论文。当前数据还从监测、流行病学和最终结果计划（SEER）数据库中提取。
对前列腺癌发生的危险因素进行综述。重点在于识别规模较大的对照研究。
前列腺癌的临床发病率正在上升。前列腺癌的危险因素似乎包括年龄、种族、家族史阳性、输精管切除术和膳食脂肪摄入。
前列腺癌似乎是内源性激素与环境影响（其中最主要的是膳食脂肪）相互作用的结果。
