Rosenthal N E, Moul D E, Hellekson C J, Oren D A, Frank A, Brainard G C, Murray M G, Wehr T A
Clinical Psychobiology Branch, DIRP, National Institute of Mental Health, Bethesda, Maryland 20892.
Neuropsychopharmacology. 1993 Feb;8(2):151-60. doi: 10.1038/npp.1993.17.
Fifty-five patients with winter seasonal affective disorder (SAD) were treated with a light visor, a newly developed portable light-delivery system, in a controlled parallel design. A dim (400 lux) visor was compared with a bright (6000 lux) visor for either 30 or 60 minutes in the morning for 1 week. Response rates for these two treatments were 36% and 56%, respectively; the duration of treatment sessions did not affect outcome. There was no evidence that the brighter visor was superior in efficacy to the dimmer one. Significantly greater relapse occurred following withdrawal of the dimmer visor. Alternative explanations for these findings are that the light visor is acting as a placebo or that it is equally effective over a wide range of intensities.
五十五名冬季季节性情感障碍（SAD）患者采用一种新开发的便携式光传输系统——光眼罩，以对照平行设计进行治疗。将昏暗（400勒克斯）眼罩与明亮（6000勒克斯）眼罩在早晨分别照射30或60分钟，持续1周。这两种治疗的有效率分别为36%和56%；治疗时长不影响疗效。没有证据表明较亮的眼罩在疗效上优于较暗的眼罩。撤掉较暗的眼罩后复发情况明显更严重。对这些发现的其他解释是，光眼罩起到了安慰剂的作用，或者在广泛的光照强度范围内其效果相同。
