胃肠道微生物群紊乱对坏死梭杆菌生物变种A粪便排泄的影响。
Effect of disturbance of the gastrointestinal microflora on the faecal excretion of Fusobacterium necrophorum biovar A.
作者信息
Smith G R, Thornton E A
机构信息
Institute of Zoology, Zoological Society of London.
出版信息
Epidemiol Infect. 1993 Apr;110(2):333-7. doi: 10.1017/s0950268800068278.
Abstract
Oral pretreatment of mice with either a mixture of kanamycin and erythromycin or metronidazole to modify the gut microflora greatly enhanced the faecal excretion of Fusobacterium necrophorum biovar A given by mouth. This lends support to the suggestion that disturbance of the gastrointestinal microflora in animals such as cattle, which often carry the organism in the rumen, may lead to intestinal multiplication and faecal excretion, thereby providing a source of infection that may lead to necrobacillosis of the body surface.
摘要
用卡那霉素和红霉素混合物或甲硝唑对小鼠进行口服预处理以改变肠道微生物群，极大地增强了经口给予的坏死梭杆菌生物变种A的粪便排泄量。这支持了这样一种观点，即在瘤胃中常携带该菌的牛等动物中，胃肠道微生物群的紊乱可能导致该菌在肠道内繁殖并随粪便排出，从而提供一个可能导致体表坏死杆菌病的感染源。
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