Kuramoto K, Matsushita S, Esaki Y, Shimada H
Tokyo Metropolitan Geriatric Hospital.
Nihon Ronen Igakkai Zasshi. 1993 Jan;30(1):35-40. doi: 10.3143/geriatrics.30.35.
The prevalence, rate of correct clinical diagnosis and mortality of cancer were analyzed in 4,894 consecutive autopsies at the Tokyo Metropolitan Geriatric Hospital from 1972 to 1990. average age and standard deviation of patients was 78.1 +/- 9.1 years. Cancer was found in 45.5% of patients of 60 years and over, and in 49.1% in men and 41.9% in women (p < 0.001). Cancer prevalence decreased with advance in age; 50.0% in the sixties, 47.9% in the seventies, 43.2% in the eighties and 39.3% in the nineties and over. Multiple cancer was found in approximately 12% of patients of 70 years and over. The top three cancer incidences were gastric cancer, 15.0%, lung cancer, 10.7% and colon cancer, 5.9% in both genders. In men, prostate cancer was next common, followed in orderly hepatic cancer, esophageal cancer, gall bladder-bile duct cancer, pancreas cancer, renal cancer and urinary bladder cancer. In women, the following order of frequency was gall bladder-bile duct cancer, uterus cancer, pancreas cancer, hepatic cancer, breast cancer, thyroid cancer, esophageal cancer, renal cancer and urinary bladder cancer. The prevalence of gastric cancer, lung cancer, hepatic cancer and esophageal cancer was significantly higher in men, while that of gall bladder-bile duct cancer was higher in women. The age-related tendencies varied among cancers of different organs. Gastric cancer increased up to the sixties in men and up to the seventies in women and leveled off after those ages. Lung cancer revealed peak prevalence in the sixties and seventies and decreased after the age of eighty.(ABSTRACT TRUNCATED AT 250 WORDS)
对1972年至1990年东京都老人医院连续4894例尸检病例的癌症患病率、临床正确诊断率及死亡率进行了分析。患者的平均年龄及标准差为78.1±9.1岁。60岁及以上患者中45.5%患有癌症,男性为49.1%,女性为41.9%(p<0.001)。癌症患病率随年龄增长而下降;60多岁患者中为50.0%,70多岁患者中为47.9%,80多岁患者中为43.2%,90岁及以上患者中为39.3%。70岁及以上患者中约12%患有多发性癌症。男女癌症发病率最高的前三位均为胃癌(15.0%)、肺癌(10.7%)和结肠癌(5.9%)。男性中,前列腺癌次之,依次为肝癌、食管癌、胆囊-胆管癌、胰腺癌、肾癌和膀胱癌。女性中,发病率依次为胆囊-胆管癌、子宫癌、胰腺癌、肝癌、乳腺癌、甲状腺癌、食管癌、肾癌和膀胱癌。胃癌、肺癌、肝癌和食管癌的患病率男性显著高于女性,而胆囊-胆管癌女性患病率更高。不同器官癌症的年龄相关趋势各不相同。男性胃癌患病率在60多岁时上升,女性在70多岁时上升,此后趋于平稳。肺癌患病率在60多岁和70多岁时达到峰值,80岁以后下降。(摘要截选至250字)