新西兰多元文化劳动力群体的血清脂质水平。

Serum lipid levels in a New Zealand multicultural workforce.

作者信息

Scragg R, Baker J, Metcalf P, Dryson E

机构信息

Department of Community Health, University of Auckland.

出版信息

N Z Med J. 1993 Mar 24;106(952):96-9.

PMID:8474725

Abstract

AIMS

To examine ethnic variations in serum lipid levels and to determine whether lipids are related to lifestyle variables in a New Zealand multicultural workforce.

METHODS

Fasting blood samples were collected from 5671 employed people for determination of serum total and HDL cholesterol, triglycerides, and LDL cholesterol. Individual exposures over the previous three months to smoking, alcohol, leisure time physical activity were recorded, and weight and height were measured to calculate body mass index (BMI).

RESULTS

Maori and Pacific Islanders had lower age-adjusted total and LDL cholesterol levels than Europeans, and these differences were increased by controlling for BMI. In contrast, age-adjusted mean (SE) HDL cholesterol levels were also lower in Maori (men = 1.17 (0.02); women = 1.38 (0.03) mmol/L) and Pacific Islanders (men = 1.17 (0.01); women = 1.30 (0.02) mmol/L) compared with Europeans (men = 1.20 (0.01); women = 1.47 (0.01) mmol/L), but when BMI, smoking and other variables were controlled, levels were significantly higher in Maori and Pacific Islanders. With serum triglycerides, the pattern was not consistent in Maori and Pacific Islanders. Age-adjusted mean levels in Maori (men = 2.25 (0.07) mmol/L; women = 1.53(0.07) mmol/L) were significantly higher (p < 0.05) than in Pacific Islanders (men = 1.82 (0.06); women = 1.34(0.05) mmol/L) of the same sex. After controlling for BMI and other variables, triglyceride levels were also significantly lower in Pacific Islanders than in Europeans and Asians. BMI and smoking were positively associated with total and LDL cholesterol and triglycerides, and negatively with HDL cholesterol, after controlling for alcohol and physical activity.

CONCLUSION

Lifestyle risk factors, particularly BMI and smoking, are strongly related to serum levels of all major lipids. Ethnic variations in coronary heart disease mortality rates in New Zealand are more consistent with ethnic variations in triglycerides than with variations in the other serum lipids.

摘要

目的

研究新西兰多元文化工作人群血清脂质水平的种族差异，并确定脂质是否与生活方式变量相关。

方法

采集5671名在职人员的空腹血样，以测定血清总胆固醇、高密度脂蛋白胆固醇、甘油三酯和低密度脂蛋白胆固醇。记录个人在过去三个月内的吸烟、饮酒、休闲时间体力活动情况，并测量体重和身高以计算体重指数（BMI）。

结果

毛利人和太平洋岛民的年龄调整后总胆固醇和低密度脂蛋白胆固醇水平低于欧洲人，在控制BMI后，这些差异更为明显。相比之下，毛利人（男性 = 1.17（0.02）；女性 = 1.38（0.03）mmol/L）和太平洋岛民（男性 = 1.17（0.01）；女性 = 1.30（0.02）mmol/L）的年龄调整后平均（SE）高密度脂蛋白胆固醇水平也低于欧洲人（男性 = 1.20（0.01）；女性 = 1.47（0.01）mmol/L），但在控制BMI、吸烟和其他变量后，毛利人和太平洋岛民的水平显著更高。对于血清甘油三酯，毛利人和太平洋岛民的情况不一致。毛利人同性别者的年龄调整后平均水平（男性 = 2.25（0.07）mmol/L；女性 = 1.53（0.07）mmol/L）显著高于（p < 0.05）太平洋岛民（男性 = 1.82（0.06）；女性 = 1.34（0.05）mmol/L）。在控制BMI和其他变量后，太平洋岛民的甘油三酯水平也显著低于欧洲人和亚洲人。在控制饮酒和体力活动后，BMI和吸烟与总胆固醇、低密度脂蛋白胆固醇和甘油三酯呈正相关，与高密度脂蛋白胆固醇呈负相关。