西班牙西北部糖尿病视网膜病变的患病率。加利西亚地区糖尿病视网膜病变的流行病学研究。I

The prevalence of diabetic retinopathy in northwest Spain. An epidemiological study of diabetic retinopathy in Galicia. I.

作者信息

Fernandez-Vigo J, Sanchez Macho J, Diaz Rey A, Barros J, Tome M, Bueno J

机构信息

Department of Ophthalmology, Hospital Clinico Universitario, School of Medicine, University of Santiago de Compostela, Spain.

出版信息

Acta Ophthalmol (Copenh). 1993 Feb;71(1):22-6. doi: 10.1111/j.1755-3768.1993.tb04954.x.

DOI:10.1111/j.1755-3768.1993.tb04954.x

PMID:8475709

Abstract

The prevalence of retinopathy was studied in a group of 1179 diabetic patients attending 11 diabetologic centres in Gallica (Northwest of Spain). The age of the patients was 61.7 +/- 13.8 years, 43.8% were males and 56.2% females. The patients had had diabetes from 8.4 +/- 7.5 years, 30.4% were being treated with insulin, and 69.6% with oral antihyperglycaemics. 16.1% were aged under 40 years at onset as against 83.9% aged over 40 years. The prevalence of retinopathy was 44.7, in the whole group. Stepwise multiple regression analysis identified treatment time since onset and age at onset as the factors affecting prevalence, which was 61.8% in the insulin-treated subgroup vs 37% among those treated with oral antihyperglycaemics (p < 0.0001). The prevalence of proliferative diabetic retinopathy was 5.8% in the whole group.

摘要

在加利西亚（西班牙西北部）11个糖尿病中心就诊的1179名糖尿病患者中，对视网膜病变的患病率进行了研究。患者年龄为61.7±13.8岁，男性占43.8%，女性占56.2%。患者患糖尿病8.4±7.5年，30.4%接受胰岛素治疗，69.6%接受口服降糖药治疗。16.1%发病年龄在40岁以下，83.9%发病年龄在40岁以上。整个组中视网膜病变的患病率为44.7%。逐步多元回归分析确定发病后的治疗时间和发病年龄是影响患病率的因素，胰岛素治疗亚组的患病率为61.8%，口服降糖药治疗组为37%（p<0.0001）。整个组中增殖性糖尿病视网膜病变的患病率为5.8%。