Siu A W, Herse P R
Department of Optometry, University of Auckland, New Zealand.
Acta Ophthalmol (Copenh). 1993 Feb;71(1):57-61. doi: 10.1111/j.1755-3768.1993.tb04960.x.
Corneal edema was induced by a 2-h closed-eye wear of a thick hydrogel contact lens. Corneal edema production and edema recovery responses were measured in the central and mid-peripheral (3 mm inferior) cornea of 10 younger (20.4 +/- 2.0 years) and 10 older (69.0 +/- 3.4 years) subjects using optical pachometry. The amount of edema produced was not significantly different between the two corneal locations nor between the two age groups. The edema recovery rates of the central and mid-peripheral cornea were not significantly different in either the younger or older group. The edema recovery rates at both corneal positions were significantly faster in the younger group than in the older group. The results of this study suggest that the mechanisms that control edema production and recovery in the inferior mid-peripheral cornea are similar to those previously described in central and temporal mid-peripheral locations. Ageing appears to influence the edema production and recovery mechanisms of both the central and mid-peripheral cornea in similar ways.
通过佩戴厚水凝胶隐形眼镜闭眼2小时诱导角膜水肿。使用光学厚度测量法在10名年轻受试者（20.4±2.0岁）和10名年长受试者（69.0±3.4岁）的中央角膜和中周边角膜（下方3毫米处）测量角膜水肿的产生和水肿恢复反应。两个角膜位置之间以及两个年龄组之间产生的水肿量没有显著差异。年轻组或年长组中，中央角膜和中周边角膜的水肿恢复率没有显著差异。两个角膜位置的水肿恢复率在年轻组中均显著快于年长组。本研究结果表明，控制下方中周边角膜水肿产生和恢复的机制与先前在中央和颞侧中周边位置所描述的机制相似。衰老似乎以相似的方式影响中央角膜和中周边角膜的水肿产生和恢复机制。
