Falor W H, Ward R M
Surg Gynecol Obstet. 1977 Apr;144(4):515-8.
In this series of 27 consecutive patients with well differentiated noninvasive carcinoma of the bladder, cytogenetic analysis repeatedly performed showed marker chromosomes in curative cytoscopic resections of 15 of the patients. In 14 of the 15 patients, recurrent carcinoma developed. Of the 12 patients without markers, one patient had a recurrence; the remaining 11 have been free of recurrence up to eight years after diagnosis. In this long term, although limited, experience with early carcinoma of the bladder, marker chromosomes have been a highly accurate prognostic aid.
在这组连续的27例高分化膀胱非浸润性癌患者中，反复进行的细胞遗传学分析显示，15例患者的根治性膀胱镜切除标本中有标记染色体。在这15例患者中，14例出现复发癌。在12例无标记染色体的患者中，1例复发；其余11例在诊断后长达8年未复发。就早期膀胱癌这一虽有限但长期的经验而言，标记染色体一直是一种高度准确的预后辅助指标。
