尼日利亚拉各斯同一组表面上健康的孕妇中人类免疫缺陷病毒（HIV）血清阳性率与乙肝表面抗原血症（HBs Ag）的比较：初步报告

A comparison of human immunodeficiency virus (HIV) seropositivity and hepatitis B surface antigenemia (HBs Ag) among the same group of apparently healthy pregnant women in Lagos, Nigeria: a preliminary report.

作者信息

Obi C L, Anyiwo C E, Nnatu S N, Agbonlahor D E, Esumeh F I, Karpas A

机构信息

Department of Biological Sciences, University of Lagos, Nigeria.

出版信息

Viral Immunol. 1993 Spring;6(1):43-7. doi: 10.1089/vim.1993.6.43.

DOI:10.1089/vim.1993.6.43

PMID:8476507

Abstract

Two hundred and fifty apparently healthy pregnant women attending the Obstetrics and Gynecology Clinic of the Lagos University Teaching Hospital (LUTH), Lagos, Nigeria were screened for a comparison of the prevalence of HIV seropositivity and hepatitis B surface antigenemia (HBs Ag) amongst them. The Karpas AIDS cell test for HIV seropositivity and Bioman Hepatitis test kits were used as described by the manufacturers. HIV seropositive cases were confirmed using the Western blot test. Results revealed that out of the 250 pregnant women screened, 2 (0.8%) and 11 (4.4%) were HIV-1 and HBs Ag seropositive, respectively. However, the same 2 pregnant women now constituting 2 (18.2%) of the 11 HBs Ag positive pregnant women were simultaneously HIV-1 seropositive. Antibody to HIV-2 was not recorded in all HIV seropositive cases. This is the first report on the simultaneous prevalence of HBs Ag and HIV seropositivity among apparently healthy pregnant women in Lagos, Nigeria.

摘要

对尼日利亚拉各斯拉各斯大学教学医院（LUTH）妇产科诊所的250名表面健康的孕妇进行了筛查，以比较她们中HIV血清阳性和乙肝表面抗原血症（HBs Ag）的患病率。按照制造商的说明，使用Karpas艾滋病细胞检测法检测HIV血清阳性，并使用Bioman肝炎检测试剂盒检测HBs Ag。HIV血清阳性病例通过蛋白质印迹法进行确认。结果显示，在筛查的250名孕妇中，分别有2名（0.8%）和11名（4.4%）为HIV-1和HBs Ag血清阳性。然而，这2名孕妇同时也是HIV-1血清阳性，她们占11名HBs Ag阳性孕妇的2名（18.2%）。在所有HIV血清阳性病例中均未检测到HIV-2抗体。这是关于尼日利亚拉各斯表面健康孕妇中HBs Ag和HIV血清阳性同时患病率的首份报告。