Settatree R S, Watkinson M
West Midlands Regional Perinatal Audit, Solihull Hospital, UK.
Br J Obstet Gynaecol. 1993 Feb;100(2):110-21. doi: 10.1111/j.1471-0528.1993.tb15204.x.
To examine problems encountered in classifying perinatal death using the systems proposed by Hey et al. (1986) and Cole et al. (1986).
451 deaths from a regional perinatal mortality survey of which 293 had a post mortem examination.
Documents from each death were reviewed by four assessors, one from each discipline, selected randomly from a pool of obstetricians, paediatricians, general practitioners and midwives. Each assessor classified the cause of death blind to the others. The degree of agreement between assessors was calculated for the full and shortened obstetric and fetal-neonatal classifications using the kappa statistic for inter-rater agreement.
The kappa statistic, which is a measure of the proportion of agreement above chance, gave a value of 0.55 for the full obstetric classification and 0.58 for the full fetal and neonatal classification when all four assessors made an assignment. An assignment was omitted in 6.2%, but the kappa value of zero for these omissions suggested that this was a nonsystematic result due to random protocol violations. The grouped (shortened) classifications generated a higher kappa value of 0.62 for the nine point obstetric system and 0.67 for the six point fetal and neonatal (New Wigglesworth) system. Post mortem had little effect on agreement. The best agreement levels observed were for congenital anomaly.
This survey highlighted the complexity of the 22 and 24 point classifications, the uneven distribution of deaths within their categories, and the variable levels of agreement between professionals classifying deaths, thus questioning the validity of individual maternity units of health districts generating local data in this degree of detail for comparative purposes in regional and national statistics. Grouping the original categories led to greater agreement particularly for the New Wigglesworth classification. The role of post mortems in clarifying the cause of fetal and neonatal death needs further investigation.
使用Hey等人(1986年)和Cole等人(1986年)提出的系统,研究围产期死亡分类中遇到的问题。
来自区域围产期死亡率调查的451例死亡病例,其中293例进行了尸检。
由四名评估人员对每例死亡病例的文件进行审查,这四名评估人员分别来自产科医生、儿科医生、全科医生和助产士群体,随机挑选,每个学科一名。每位评估人员在对其他人员不知情的情况下对死亡原因进行分类。使用评估者间一致性的kappa统计量,计算评估人员在完整和简化的产科及胎儿-新生儿分类中的一致程度。
kappa统计量是衡量高于随机一致性比例的指标,当所有四名评估人员都进行赋值时,完整产科分类的kappa值为0.55,完整胎儿和新生儿分类的kappa值为0.58。有6.2%的病例未进行赋值,但这些未赋值病例的kappa值为零,表明这是由于随机违反方案导致的非系统性结果。分组(简化)分类在九点产科系统中产生了更高的kappa值0.62,在六点胎儿和新生儿(新威格尔斯沃思)系统中为0.67。尸检对一致性影响不大。观察到的最佳一致水平是先天性异常。
本次调查突出了22点和24点分类的复杂性、各类别内死亡分布不均以及死亡分类专业人员之间的一致程度参差不齐,从而对健康区各产科单位为区域和国家统计中的比较目的生成如此详细的本地数据的有效性提出质疑。对原始类别进行分组导致了更高的一致性,特别是对于新威格尔斯沃思分类。尸检在明确胎儿和新生儿死亡原因方面的作用需要进一步研究。