Hochman L G, Scher R K, Meyerson M S
Department of Dermatology, College of Physicians and Surgeons of Columbia University, New York, New York.
Cutis. 1993 Apr;51(4):303-5.
A recent study from Switzerland demonstrated a 25 percent increase in nail plate thickness in patients with brittle nails who received biotin supplementation. Analysis of all visits to a nail consultation practice over a six-month period revealed forty-four patients with this condition who had been prescribed the B-complex vitamin biotin. Of these, thirty-five who took daily supplementation were subjectively evaluated. Twenty-two of thirty-five (63 percent) showed clinical improvement and thirteen (37 percent) reported no change in their condition. The results of this small, retrospective study suggest a positive response to biotin in the treatment of brittle nails in some patients.
瑞士最近的一项研究表明，补充生物素的脆甲症患者指甲厚度增加了25%。对一家指甲咨询诊所六个月内的所有就诊记录进行分析后发现，有44名患有此病的患者被开了复合维生素B生物素。其中，35名每日接受补充治疗的患者接受了主观评估。35名患者中有22名（63%）显示出临床改善，13名（37%）报告病情无变化。这项小型回顾性研究的结果表明，部分患者在使用生物素治疗脆甲症方面有积极反应。
