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兔源肠致病性大肠杆菌菌株中eae序列的鉴定。

Identification of eae sequences in enteropathogenic Escherichia coli strains from rabbits.

作者信息

Pohl P H, Peeters J E, Jacquemin E R, Lintermans P F, Mainil J G

机构信息

National Institute of Veterinary Research, Brussels, Belgium.

出版信息

Infect Immun. 1993 May;61(5):2203-6. doi: 10.1128/iai.61.5.2203-2206.1993.

Abstract

DNA sequences coding for attachment and for verotoxin production were investigated in a collection of enteropathogenic Escherichia coli strains from rabbits. All of the strains produced diarrhea after experimental infection, attached to the brush borders of the intestinal lining, and possessed homology to the eae probe, whereas strains isolated from healthy rabbits did not. Sequences homologous to the AF/R1 fimbriae of strain RDEC-1 were not found. One strain reacted with the probe for the Shiga-like toxin type I gene.

摘要

对一组来自兔子的肠致病性大肠杆菌菌株中编码黏附及志贺毒素产生的DNA序列进行了研究。所有菌株在实验性感染后均引发腹泻,附着于肠黏膜的刷状缘,并与eae探针具有同源性,而从健康兔子分离出的菌株则不然。未发现与RDEC - 1菌株的AF/R1菌毛同源的序列。有一个菌株与I型志贺样毒素基因的探针发生反应。

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