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1989 - 1991年乌干达坎帕拉的癌症:艾滋病时代的发病率变化

Cancer in Kampala, Uganda, in 1989-91: changes in incidence in the era of AIDS.

作者信息

Wabinga H R, Parkin D M, Wabwire-Mangen F, Mugerwa J W

机构信息

Department of Pathology, Makerere Medical School, Kampala, Uganda.

出版信息

Int J Cancer. 1993 Apr 22;54(1):26-36. doi: 10.1002/ijc.2910540106.

DOI:10.1002/ijc.2910540106
PMID:8478145
Abstract

Re-establishment of the cancer registry in Kyadondo County, Uganda, has allowed estimation of incidence rates for the period September 1989 to December 1991. The results are compared with earlier data from the same area, and from other African cancer registries. The most striking feature is the emergence of Kaposi's sarcoma as the leading cancer in males (almost half of all registered cases) and the second most frequent (17.9%) in females. This parallels the evolution of the epidemic of AIDS. There were also marked increases in the incidence of both oesophageal and prostatic carcinoma, while the incidence of cancer of the penis and the urinary bladder declined, possibly as a result of improved standards of hygiene. In females, the incidence of cancer of the cervix has more than doubled since the 1950s, and is now among the highest recorded in the African continent.

摘要

乌干达卡延东多县重新建立了癌症登记处,得以估算1989年9月至1991年12月期间的发病率。研究结果与该地区早期数据以及其他非洲癌症登记处的数据进行了比较。最显著的特征是卡波西肉瘤成为男性中最主要的癌症(几乎占所有登记病例的一半),在女性中则是第二常见的癌症(占17.9%)。这与艾滋病流行的演变情况相似。食管癌和前列腺癌的发病率也显著上升,而阴茎癌和膀胱癌的发病率下降,这可能是卫生标准提高的结果。在女性中,自20世纪50年代以来宫颈癌的发病率增加了一倍多,目前是非洲大陆有记录以来最高的发病率之一。

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