Ueda M, Abe Y, Fujiwara H, Fujimoto W, Arakawa K, Arata J, Yoshioka T, Tomoda J, Katayama H
Department of Dermatology, Okayama University Medical School, Japan.
J Dermatol. 1993 Mar;20(3):180-4. doi: 10.1111/j.1346-8138.1993.tb03856.x.
A 64-year-old woman with CREST syndrome developed prominent telangiectases mimicking hereditary hemorrhagic telangiectasia (HHT) of Osler-Rendu-Weber. We have been following her since she first came to us with discrete telangiectatic mats and Raynaud's phenomenon 11 years ago. Telangiectatic lesions have been seen on her larynx and esophagus in addition to commonly affected sites. She has experienced spontaneous epistaxis and marked bleeding from the lesions on her lips, oral mucous membrane, and soles. This case illuminates new aspects of telangiectasia in CREST syndrome.
一名患有CREST综合征的64岁女性出现了明显的毛细血管扩张，酷似Osler-Rendu-Weber遗传性出血性毛细血管扩张症（HHT）。11年前，她首次因散在的毛细血管扩张斑和雷诺现象前来就诊，此后我们一直在对她进行随访。除了常见的受累部位外，在她的喉部和食管也发现了毛细血管扩张性病变。她曾经历过自发性鼻出血，嘴唇、口腔黏膜和脚底的病变处有明显出血。该病例揭示了CREST综合征中毛细血管扩张的新情况。
