Freedman A L, Costa Neto F, Mehringer C M, Rajfer J
Department of Surgery, UCLA School of Medicine.
J Urol. 1993 May;149(5 Pt 2):1301-3. doi: 10.1016/s0022-5347(17)36374-7.
Between 1986 and 1991, 46 men with organic impotence documented by dynamic pharmacocavernosometry and cavernosography to have venous leakage underwent penile vein ligation. Despite initial improvement in erections allowing normal intercourse in 34 men (74%) within the first 6 months, long-term (more than 12 months) evaluation revealed sustained potency without adjunctive therapy in only 11 (24%). Of the remaining 35 men 6 (13%) progressed to a penile prosthesis, 8 (17%) required intracavernous vasoactive injection therapy and 21 (46%) have not sought further therapy despite continued impotence. Of the 14 patients who had isolated distal leakage 6 (43%) had sustained erectile function while only 5 of the 32 patients (16%) with proximal leakage maintained potency. Associated complications included penile shortening in 20 (43%) and penile hypoesthesia in 9 men (20%). Therefore, we conclude that the long-term success of penile vein ligation is poor, with only 24% of the patients able to have normal intercourse more than 1 year later, although those patients with distal penile shaft leakage appear to have a greater chance of success than those with more proximal leakage.
在1986年至1991年期间，46名经动态海绵体测压和海绵体造影证实存在静脉漏的器质性阳痿男性接受了阴茎静脉结扎术。尽管最初有改善，34名男性（74%）在头6个月内能够进行正常性交，但长期（超过12个月）评估显示，仅11名男性（24%）在无辅助治疗的情况下维持了性功能。其余35名男性中，6名（13%）进展为阴茎假体植入，8名（17%）需要海绵体内血管活性药物注射治疗，21名（46%）尽管仍存在阳痿但未寻求进一步治疗。在14名单纯远端漏血的患者中，6名（43%）维持了勃起功能，而在32名近端漏血的患者中，只有5名（16%）维持了性功能。相关并发症包括20名（43%）阴茎缩短和9名男性（20%）阴茎感觉减退。因此，我们得出结论，阴茎静脉结扎术的长期成功率较低，只有24%的患者在1年多后能够进行正常性交，尽管阴茎远端漏血的患者似乎比近端漏血的患者有更大的成功机会。
