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[羟乙基淀粉、右旋糖酐60和血液快速输注对术后患者的不同循环影响]

[Varied circulatory effects after rapid infusion of hydroxyethyl starch, dextran 60 and blood in the postoperative patient].

作者信息

Eisele R, Birnbaum D, Büscher D, Kötter D, Nasseri M

出版信息

Infusionsther Klin Ernahr. 1979;6(1):43-8.

PMID:84791
Abstract

The acute hemodynamic effects which occur after a quick infusion (500 ml per 10 minutes) of hydroxyethyl starch, dextran 60 or autologous blood with identical hematocrit were studied in three groups of 10 patients each on the first day after laparotomy. If blood is infused there is only a moderate increase of the total perfusion (+18%) observed, however hydroxyethyl starch or dextran 60 infusions result in a striking increase of the cardiac output (+34%, +44%, respectively). There is no significant difference among the latter two groups. Thus, hydroxyethyl starch as well as dextran 60 can be considered as a potent volume substitute, if an acute effectiveness is wanted.

摘要

在剖腹手术后的第一天,对三组患者(每组10例)进行了研究,快速输注(每10分钟500毫升)羟乙基淀粉、右旋糖酐60或具有相同血细胞比容的自体血后所产生的急性血流动力学效应。如果输注血液,观察到总灌注仅适度增加(+18%),然而输注羟乙基淀粉或右旋糖酐60会导致心输出量显著增加(分别为+34%、+44%)。后两组之间没有显著差异。因此,如果需要急性起效,羟乙基淀粉以及右旋糖酐60都可被视为有效的容量替代物。

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