[年轻囊性纤维化患者的肺部高分辨率计算机断层扫描]

[High-resolution computed tomography of the lung in young patients with cystic fibrosis].

作者信息

Helbich T, Stiglbauer R, Breitenseher M, Eichler I, Götz M, Schurawitzki H

机构信息

Universitätsklinik für Radiodiagnostik, Allgemeines Krankenhaus, Ludwig-Boltzmann-Institut für radiologisch-physikalische Tumordiagnostik, Wien.

出版信息

Radiologe. 1993 Mar;33(3):142-6.

PMID:8480022

Abstract

In a prospective study we proved the value of high-resolution computed tomography (HRCT) and the CT scoring system developed by Stiglbauer et al. on 47 young patients suffering from cystic fibrosis (CF) (median age: 10.1 years). The most frequent pulmonary finding was bronchial wall thickening (BWT) in 43 patients (94.6%), followed by bronchiectasis (BE) in 36 patients (79.2%). A less frequent finding was ill-defined patchy consolidation (39.6%). We found an almost even distribution of BWT and BE in the upper and lower lobes of the lung. These two findings were scored according to their severity and extent. The maximum possible score for BWT and BE was 72 in a single patient. For both the overall score was 19.9 +/- 11.1. A statistically significant correlation of the CT scoring system with the lung function tests FEV1/FVC (P = 0.03) and MEF50 (P = 0.02) was found. The results of HRCT and the CT scoring system were shown to be valuable methods in the assessment of pulmonary changes, in young patients suffering from CF.

摘要

在一项前瞻性研究中，我们证实了高分辨率计算机断层扫描（HRCT）以及由施蒂格鲍尔等人开发的CT评分系统对47例囊性纤维化（CF）年轻患者（中位年龄：10.1岁）的价值。最常见的肺部表现是43例患者（94.6%）出现支气管壁增厚（BWT），其次是36例患者（79.2%）出现支气管扩张（BE）。不太常见的表现是边界不清的斑片状实变（39.6%）。我们发现BWT和BE在肺的上叶和下叶分布几乎均匀。根据其严重程度和范围对这两种表现进行评分。单个患者BWT和BE的最高可能评分为72分。两者的总体评分为19.9±11.1。发现CT评分系统与肺功能测试FEV1/FVC（P = 0.03）和MEF50（P = 0.02）存在统计学显著相关性。HRCT和CT评分系统的结果被证明是评估CF年轻患者肺部变化的有价值方法。