Fujita N, Duerinekx A J, Higgins C B
Department of Radiology, University of California, San Francisco 94143-0628.
Am Heart J. 1993 May;125(5 Pt 1):1337-45. doi: 10.1016/0002-8703(93)91004-x.
We measured the variation of end-systolic wall stress and its relation to regional ejection fraction in short-axis planes through the left ventricle in normal subjects and in patients with dilated cardiomyopathy (DCM) by cine magnetic resonance imaging. There was a gradual increase in end-systolic wall stress but a gradual decrease in ejection fraction from apex to base in normal subjects (14 +/- 6 to 52 +/- 15 kdyne/cm2, 78% +/- 12% to 62% +/- 8%) and in patients with DCM (49 +/- 28 to 130 +/- 30 kdyne/cm2, 40 +/- 18 to 23% +/- 9%). The end-systolic wall stress in patients with DCM was higher than in normal subjects at every level (p < 0.01). We conclude that there is a variation in end-systolic wall stress in both normal subjects and patients with DCM with regional ejection fraction inversely related to regional end-systolic wall stress.
我们通过电影磁共振成像测量了正常受试者和扩张型心肌病（DCM）患者左心室短轴平面内心脏收缩末期壁应力的变化及其与局部射血分数的关系。正常受试者（14±6至52±15达因/平方厘米，78%±12%至62%±8%）和DCM患者（49±28至130±30达因/平方厘米，40±18至23%±9%）从心尖到心底心脏收缩末期壁应力逐渐增加，但射血分数逐渐降低。DCM患者在每个层面的心脏收缩末期壁应力均高于正常受试者（p<0.01）。我们得出结论，正常受试者和DCM患者的心脏收缩末期壁应力均存在变化，局部射血分数与局部心脏收缩末期壁应力呈负相关。
