Saló J, Nomdedeu B, Bruguera M, Ordi J, Ginès P, Castells A, Vilella A, Rodés J
Hematology Department, Hospital Clínic i Provincial, Universitat de Barcelona, Catalunya, Spain.
Am J Gastroenterol. 1993 May;88(5):774-6.
Acute hepatic failure secondary to involvement of the liver by hematologic malignancies is a very uncommon condition, and usually has a fatal prognosis. We describe the case of a woman who developed acute hepatic failure due to infiltration by a non-Hodgkin's lymphoma 18 yr after the initial diagnosis of a nodular-type lymphocytic lymphoma, while she was apparently in remission. Early diagnosis was achieved through liver biopsy; therefore, rapid administration of chemotherapy allowed her complete recovery. Hepatic biopsy may provide a diagnosis in patients in whom the etiology of liver failure is unknown, thus establishing the possible need for specific treatment.
血液系统恶性肿瘤累及肝脏继发的急性肝衰竭是一种非常罕见的病症，通常预后不良。我们描述了一例女性患者的病例，该患者在最初诊断为结节型淋巴细胞淋巴瘤18年后，表面上处于缓解期时，因非霍奇金淋巴瘤浸润而发生急性肝衰竭。通过肝活检实现了早期诊断；因此，快速给予化疗使她完全康复。肝活检可为肝衰竭病因不明的患者提供诊断，从而确定可能需要的特异性治疗。
