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慢性淋巴细胞白血病致急性肝衰竭 1 例报告并文献复习

Acute liver failure because of chronic lymphocytic leukemia: case report and review of the literature.

机构信息

Department of Medicine, McGill University, Montreal, QC.

出版信息

Curr Oncol. 2011 Jan;18(1):39-42. doi: 10.3747/co.v18i1.756.

Abstract

Infiltration of the liver by hematologic malignancies is an uncommon cause of liver failure. B-Cell chronic lymphocytic leukemia (cll) is a usually indolent disease that may infiltrate the liver, but based on a review of the literature, has never been reported to induce acute liver failure. Here, we describe the case of a 78-year-old woman with acute liver failure secondary to infiltration with cll being unresponsive to chemotherapy and causing death. This case is notable because of its atypical presentation and ultimate poor prognosis.

摘要

血液系统恶性肿瘤浸润肝脏是肝衰竭的一个不常见原因。B 细胞慢性淋巴细胞白血病(cll)通常是一种惰性疾病,可能会浸润肝脏,但根据文献回顾,从未有报道称其会导致急性肝衰竭。在此,我们描述了一例 78 岁女性因 cll 浸润导致急性肝衰竭的病例,该患者对化疗无反应并最终死亡。该病例的特点是其表现不典型且最终预后不良。

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