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抗体介导对刚地弓形虫体液免疫反应的细胞水平抑制动力学。

Kinetics of antibody mediated suppression of humoral immune response to Toxoplasma gondii at a cellular level.

作者信息

Masihi K N, Werner H

出版信息

Zentralbl Bakteriol Orig A. 1977;237(2-3):405-10.

PMID:848221
Abstract

The effect of passively transferred Toxoplasma gondii antiserum was examined at a cellular level by rosette forming cell response in NMRI mouse spleen. The initial number of responding rosette forming cells was decreased in antibody treated animals; However, their rate of proliferation in comparison to untreated group was not significantly affected. Almost similar response could be obtained by injecting low 5 x 10(4) Toxoplasma dose alone or a combination of passive antibody and higher antigen dose of 1 x 10(6) parasites.

摘要

通过检测NMRI小鼠脾脏中形成玫瑰花结细胞的反应,在细胞水平上研究了被动转移的弓形虫抗血清的作用。在接受抗体处理的动物中,反应性玫瑰花结形成细胞的初始数量减少;然而,与未处理组相比,它们的增殖速率没有受到显著影响。单独注射低剂量5×10⁴个弓形虫或被动抗体与高剂量1×10⁶个寄生虫抗原的组合,可获得几乎相似的反应。

相似文献

1
Kinetics of antibody mediated suppression of humoral immune response to Toxoplasma gondii at a cellular level.抗体介导对刚地弓形虫体液免疫反应的细胞水平抑制动力学。
Zentralbl Bakteriol Orig A. 1977;237(2-3):405-10.
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The effect of passively transferred heterologous serum on Toxoplasma gondii in NMRI mice. Influence of the treatment on course of infection and cyst formation.被动转移的异种血清对NMRI小鼠体内刚地弓形虫的影响。该治疗对感染进程和包囊形成的影响。
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Specificity of the passive antibody-induced suppression of the humoral immune response of mice to surface antigens on human cells.被动抗体诱导小鼠对人细胞表面抗原的体液免疫应答抑制的特异性。
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Protection against experimental toxoplasmosis by adoptive immunotherapy.通过过继免疫疗法预防实验性弓形虫病。
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IgG antibody suppression of the IgM antibody response to Toxoplasma gondii in newborn rabbits.新生兔中IgG抗体对弓形虫IgM抗体反应的抑制作用。
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Suppression and enhancement of humoral immune response to Toxoplasma gondii by passive antibody.被动抗体对弓形虫体液免疫反应的抑制与增强作用
Experientia. 1977 Dec 15;33(12):1586-7. doi: 10.1007/BF01934012.