帕金森病中运动方向和幅度的编码：它们是否受到不同程度的损害（或不重要）？
Coding of movement direction and amplitude in Parkinson's disease: are they differentially impaired (or unimportant)?
作者信息
Jones D L, Phillips J G, Bradshaw J L, Iansek R, Bradshaw J A
机构信息
Department of Psychology, Monash University, Melbourne, Australia.
出版信息
J Neurol Neurosurg Psychiatry. 1993 Apr;56(4):419-22. doi: 10.1136/jnnp.56.4.419.
A recent study suggested that the preparation of movement direction, but not amplitude, may be selectively impaired by Parkinson's disease (PD). The authors examined the reprogramming of direction only, amplitude only, and direction and amplitude together, and included a control condition in which neither parameter was reprogrammed. The findings suggested that neither direction nor amplitude coding was differentially impaired in PD. Thus the structures affected by PD may not be uniquely involved in specifying only the direction or the amplitude of future movements; these structures probably have more complex higher-level roles.
最近的一项研究表明，帕金森病（PD）可能会选择性地损害运动方向的准备，而不是运动幅度的准备。作者仅研究了方向的重新编程、仅幅度的重新编程以及方向和幅度一起的重新编程，并纳入了一个不重新编程任何参数的对照条件。研究结果表明，PD患者在方向编码和幅度编码方面均未受到差异性损害。因此，受PD影响的结构可能并非仅独特地参与确定未来运动的方向或幅度；这些结构可能具有更复杂的高级功能。
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