Hallett M, Khoshbin S
Brain. 1980 Jun;103(2):301-14. doi: 10.1093/brain/103.2.301.
Patients with Parkinson's disease were asked to make ballistic elbow flexion movements of 10, 20 and 40 degrees. Normal subjects made all these movements in the same amount of time with a single 'triphasic' EMG pattern of successive bursts in biceps, triceps and biceps. Almost all the patients made some movements requiring additional cycles of alternating biceps and triceps activity. Most of the patients exhibited at least one example of a longer movement taking more cycles than a shorter movement. It is argued that this behaviour explains previous kinematic analyses of movement in patients with Parkinson's disease and represents a physiological mechanism of bradykinesia. In part on the basis of the data presented here, it is suggested that a normal role of the basal ganglia in movement is to energize the appropriate muscles required to make the movement.
帕金森病患者被要求进行10度、20度和40度的快速肘部屈曲动作。正常受试者在相同时间内完成所有这些动作，肱二头肌、肱三头肌和肱二头肌呈现单一的“三相”肌电图模式，即连续爆发。几乎所有患者都进行了一些需要肱二头肌和肱三头肌交替活动的额外循环的动作。大多数患者至少有一个例子表明，较长的动作比较短的动作需要更多的循环。有人认为，这种行为解释了先前对帕金森病患者运动的运动学分析，并代表了运动迟缓的一种生理机制。部分基于此处给出的数据，有人提出基底神经节在运动中的正常作用是为进行运动所需的适当肌肉提供能量。
