Friedberg M A, Schwartz J C, Feinman M C, Pilkerton A R, Barth W F, Perman K I
Washington National Eye Center, DC.
Ophthalmic Surg. 1993 Mar;24(3):203-5.
We describe a patient with systemic lupus erythematosus who developed myelopathy, optic neuropathy, retinopathy, and aseptic meningitis unresponsive to immunosuppressive and antimicrobial therapy. Although cultures and brain biopsy were unrevealing, a Herpes virus was suggested by retinal biopsy. The patient recovered dramatically after institution of acyclovir therapy and optic-nerve-sheath decompression. This case demonstrates that herpetic retinitis can occur in an iatrogenically suppressed host and underscores the value of tissue diagnosis.
我们描述了一名系统性红斑狼疮患者，该患者出现了脊髓病、视神经病变、视网膜病变和无菌性脑膜炎，对免疫抑制和抗菌治疗均无反应。尽管培养和脑活检未发现异常，但视网膜活检提示为疱疹病毒感染。给予阿昔洛韦治疗和视神经鞘减压术后，患者病情显著好转。该病例表明，疱疹性视网膜炎可发生在医源性免疫抑制宿主中，并强调了组织诊断的价值。
