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Acta Vet Scand. 1977;18(1):31-9. doi: 10.1186/BF03548463.
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本文引用的文献

1
Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data.骨关节炎患者髋关节关节软骨的生化与代谢异常。II. 形态学与生化及代谢数据的相关性
J Bone Joint Surg Am. 1971 Apr;53(3):523-37.
2
Epiphyseal plate injury in the dog: a radiographic study of growth disturbance in the forelimb.犬的骨骺板损伤:前肢生长紊乱的影像学研究
J Small Anim Pract. 1971 Jan;12(1):19-36. doi: 10.1111/j.1748-5827.1971.tb05631.x.
3
[Ulnar dysplasia in the basset hound].[巴吉度猎犬的尺骨发育不全]
Schweiz Arch Tierheilkd. 1974 Jun;116(6):285-94.
4
Chemical basis for the histological use of safranin O in the study of articular cartilage.番红O在关节软骨研究中组织学应用的化学基础。
J Bone Joint Surg Am. 1971 Jan;53(1):69-82.

巴吉度猎犬尺骨的软骨内骨发育异常。

Dysostosis enchondralis of the ulnar bone in the basset hound.

作者信息

Rasmussen P G, Reimann I

出版信息

Acta Vet Scand. 1977;18(1):31-9. doi: 10.1186/BF03548463.

DOI:10.1186/BF03548463
PMID:848404
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8377620/
Abstract

Ninety-four Basset Hounds were examined for the clinical features, the radiographical changes and the nutritional and hereditary possibilities connected with the development of decreased longitudinal growth of the ulnar bone. In six puppies the possibility was examined of the development of the disease being due to overloading of the foreleg. Ten of the dogs were examined for gross pathology and 4 by histology post mortem. Clinical symptoms and radiographical changes were not seen until the age of 31/2 months. In all cases there were broadening of the joint space in the elbow joint and degeneration of the articular cartilage at the semilunar notch. An abnormally broad and irregular growth plate was seen in the affected young dogs, and histology revealed obvious abnormalities in the growth plate located in the zone of resting cartilage indicating degenerative disturbances in the cartilage. There were no signs of rickets, and it was not possible to demonstrate that the disease was caused by misleading. It is concluded that the disease corresponds to similar anomalies found in the other chondrodystrophic breeds of dogs, and it is suggested that the decreased growth of the ulnar bone may be hereditary.

摘要

对94只巴吉度猎犬进行了检查,以了解与尺骨纵向生长减少相关的临床特征、影像学变化以及营养和遗传因素。对6只幼犬研究了疾病发展是否由于前肢负荷过重。对10只犬进行了大体病理学检查,4只犬死后进行了组织学检查。直到3个半月龄才出现临床症状和影像学变化。所有病例中,肘关节间隙增宽,半月切迹处关节软骨退变。在患病幼犬中可见生长板异常宽阔且不规则,组织学显示位于静止软骨区的生长板有明显异常,提示软骨发生退行性紊乱。没有佝偻病迹象,也无法证明该疾病是由误导引起的。结论是该疾病与在其他软骨发育不良犬种中发现的类似异常相符,提示尺骨生长减少可能具有遗传性。