Goldberg C J, Dowling F E, Fogarty E E
Children's Research Centre, Our Lady's Hospital for Sick Children, Dublin, Ireland.
Spine (Phila Pa 1976). 1993 Apr;18(5):529-35. doi: 10.1097/00007632-199304000-00003.
Growth has long been known to be relevant to the development and prognosis of spinal deformity and abnormalities have been considered in the etiology of idiopathic scoliosis. Age at menarche, as an indicator of puberty, in 303 girls with idiopathic scoliosis 10 degrees or more from the Dublin school screening program was 13.13 years, 0.39 years earlier than the national mean for Irish girls. This difference is statistically significant (P < 0.01). The heights of 214 of these girls aged 10-15.5 years at diagnosis and at least 14 years at follow-up, after a minimum 6 months, were compared with the national standards. It was found that, although those diagnosed at a younger age were generally taller than their peers, this was not true for those diagnosed at a later age or for anyone at final follow-up. This points to an early pubertal growth spurt in girls with adolescent idiopathic scoliosis but not to any outright abnormality of growth or development.
长期以来,人们一直认为生长与脊柱畸形的发展和预后相关,并且特发性脊柱侧凸的病因中也考虑到了异常情况。月经初潮年龄作为青春期的一个指标,在都柏林学校筛查项目中303名特发性脊柱侧凸度数在10度及以上的女孩中为13.13岁,比爱尔兰女孩的全国平均年龄早0.39岁。这种差异具有统计学意义(P < 0.01)。将其中214名在诊断时年龄为10 - 15.5岁且随访时至少14岁(随访时间至少6个月)的女孩的身高与国家标准进行了比较。结果发现,虽然那些在较年轻时被诊断出的女孩通常比同龄人高,但对于那些在较晚时被诊断出的女孩或最终随访时的任何人来说并非如此。这表明青春期特发性脊柱侧凸女孩存在青春期早期生长突增,但并非生长或发育存在任何明显异常。