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地中海城镇学童运动诱发气道狭窄的患病率

Prevalence of exercise-induced airway narrowing in schoolchildren from a Mediterranean town.

作者信息

Bardagi S, Agudo A, Gonzalez C A, Romero P V

机构信息

Department of Medicine, Hospital de St. Jaume i Sta. Magdalena, Mataro, Spain.

出版信息

Am Rev Respir Dis. 1993 May;147(5):1112-5. doi: 10.1164/ajrccm/147.5.1112.

Abstract

A cross-sectional study was carried out on a random sample of 2,216 schoolchildren 9 to 14 yr of age to determine the prevalence of exercise-induced airway narrowing (EIAN) in a Mediterranean town (Mataró). A complementary case-control study measured the association between EIAN and respiratory symptoms. A free-running test was performed during school time. Peak expiratory flow rate (PEFR) was measured at rest and at 2, 5, 10, and 15 min after exercise. A total of 136 of 2,056 satisfactory runs showed a decrease of PEFR equal to or higher than 15% at each of these times after exercise. Five more children developed wheezing during running and were considered to have EIAN. Prevalence of EIAN was 6.9% (95% CI = 5.9 to 7.9). Prevalence decreased progressively with age. No sex difference was found. In the case-control study a questionnaire of respiratory symptoms was applied to the mothers of hyperresponsive children, as well as to two matched control subjects for each case. Questionnaire analysis showed a strong association between EIAN and respiratory symptoms or rhinitis. Association with bronchitis before 2 yr of age and parental asthma was less but significant.

摘要

对来自地中海城镇(马塔罗)的2216名9至14岁学童的随机样本进行了一项横断面研究,以确定运动诱发的气道狭窄(EIAN)的患病率。一项补充性病例对照研究测量了EIAN与呼吸道症状之间的关联。在上学时间进行了自由跑步测试。在休息时以及运动后2、5、10和15分钟测量呼气峰值流速(PEFR)。在2056次满意的跑步中,共有136次在运动后这些时间点的每次测量中显示PEFR下降等于或高于15%。另外有5名儿童在跑步过程中出现喘息,被认为患有EIAN。EIAN的患病率为6.9%(95%CI = 5.9至7.9)。患病率随年龄逐渐降低。未发现性别差异。在病例对照研究中,对反应性过高儿童的母亲以及每个病例的两名匹配对照受试者进行了呼吸道症状问卷调查。问卷分析显示EIAN与呼吸道症状或鼻炎之间存在密切关联。与2岁前的支气管炎和父母哮喘的关联较小但具有显著性。

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