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交感性眼炎中Dalen-Fuchs结节的荧光素血管造影表现。

Fluorescein angiographic appearance of Dalen-Fuchs nodules in sympathetic ophthalmia.

作者信息

Allinson R W, Le T D, Kramer T R, Snyder R W

机构信息

Department of Ophthalmology, University of Arizona, Tucson 85724.

出版信息

Ann Ophthalmol. 1993 Apr;25(4):152-6.

PMID:8484659
Abstract

A case of sympathetic ophthalmia is presented in which a single lesion located posteriorly at the level of the retinal pigment epithelium caused a serous macular detachment. We believe that this lesion represented an atypical Dalen-Fuchs nodule. Most reports of the fluorescein angiographic appearance of Dalen-Fuchs nodules describe multiple sites of choroidal leakage during the early phases, which may coalesce during the late phases of the angiogram. The lesion we detected was hypofluorescent in early phases of the fluorescein angiogram and showed late staining. The early hypofluorescence seen in the lesion may be explained by an intact retinal pigment epithelium over the presumed Dalen-Fuchs nodule, blockage of choroidal fluorescence by the nodule, and areas of granulomatous inflammation in the inner choroid and choriocapillaris. The staining in the late phases of the fluorescein angiogram may be explained by accumulation of fluorescein into the presumed Dalen-Fuchs nodule.

摘要

本文报告一例交感性眼炎,其中一个位于视网膜色素上皮水平后部的单一病变导致了浆液性黄斑脱离。我们认为这个病变代表了一个非典型的达伦-富克斯结节。大多数关于达伦-富克斯结节荧光素血管造影表现的报告描述了早期脉络膜渗漏的多个部位,这些部位在血管造影后期可能融合。我们检测到的病变在荧光素血管造影早期呈低荧光,并显示晚期染色。病变早期出现的低荧光可能是由于推测的达伦-富克斯结节上方的视网膜色素上皮完整、结节对脉络膜荧光的遮挡以及脉络膜内层和脉络膜毛细血管的肉芽肿性炎症区域所致。荧光素血管造影后期的染色可能是由于荧光素在推测的达伦-富克斯结节内积聚所致。

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Fluorescein angiographic appearance of Dalen-Fuchs nodules in sympathetic ophthalmia.交感性眼炎中Dalen-Fuchs结节的荧光素血管造影表现。
Ann Ophthalmol. 1993 Apr;25(4):152-6.
2
Morphological variation of Dalén-Fuchs nodules in sympathetic ophthalmia.交感性眼炎中达伦-富克斯结节的形态学变异
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Arch Ophthalmol. 1984 Feb;102(2):232-5. doi: 10.1001/archopht.1984.01040030182022.
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Indocyanine green angiographic findings of Dalen-Fuchs nodules in Vogt-Koyanagi-Harada disease.葡萄膜大脑炎中Dalen-Fuchs结节的吲哚菁绿血管造影表现
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Depigmented atrophic lesions in sunset glow fundi of Vogt-Koyanagi-Harada disease.Vogt-小柳-原田病晚霞样眼底的色素脱失萎缩性病变。
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引用本文的文献

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Indian J Ophthalmol. 2019 Jul;67(7):1219-1221. doi: 10.4103/ijo.IJO_409_19.
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Indocyanine green angiographic findings of Dalen-Fuchs nodules in Vogt-Koyanagi-Harada disease.葡萄膜大脑炎中Dalen-Fuchs结节的吲哚菁绿血管造影表现
Graefes Arch Clin Exp Ophthalmol. 2007 Jul;245(7):937-40. doi: 10.1007/s00417-006-0511-3. Epub 2007 Jan 12.
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Sympathetic ophthalmia: an autoimmune ocular inflammatory disease.
交感性眼炎:一种自身免疫性眼部炎性疾病。
Springer Semin Immunopathol. 1999;21(2):125-34. doi: 10.1007/BF00810245.