Hsiao S, Fan R J
Department of Psychology, University of Arizona.
Behav Neurosci. 1993 Apr;107(2):317-26. doi: 10.1037//0735-7044.107.2.317.
Effects of sweet and bitter tastes on ingestion were studied by timing licking responses. Twelve water-deprived rats were given 15-min access to sucrose (S) solutions (0.00%, 1.25%, 2.50%, and 5.00%) with and without quinine (0.01%) and to quinine (Q) solutions (0.00%, 0.0025%, 0.005%, and 0.01%) with and without sucrose (5.00%). Volume ingested and number of licks increased with S and decreased with Q. In response to S, the number of bursts increased, and interlick intervals lengthened. In response to Q, licks to ingest 1 ml of solution, burst number, and percentage of slow licks increased, and burst size decreased. When Q and S were mixed in the same solution, the pattern of ingestive responses manifested attributes of both tastes. Results suggest 2 separate, parallel systems that operate simultaneously to govern rats' licking behavior. One system expresses the effect of S on the pattern of ingestion and the other expresses the effects of Q.
通过记录舔舐反应的时间来研究甜味和苦味对摄食的影响。对12只禁水的大鼠给予15分钟时间，让它们接触含有和不含奎宁（0.01%）的蔗糖（S）溶液（0.00%、1.25%、2.50%和5.00%），以及含有和不含蔗糖（5.00%）的奎宁（Q）溶液（0.00%、0.0025%、0.005%和0.01%）。随着蔗糖浓度增加，摄入的液体量和舔舐次数增加；随着奎宁浓度增加，摄入的液体量和舔舐次数减少。对蔗糖的反应中，爆发次数增加，舔舐间隔延长。对奎宁的反应中，摄入1毫升溶液的舔舐次数、爆发次数和缓慢舔舐的百分比增加，爆发规模减小。当奎宁和蔗糖混合在同一溶液中时，摄食反应模式表现出两种味道的特征。结果表明存在两个独立的、并行的系统，它们同时运作以控制大鼠的舔舐行为。一个系统表现蔗糖对摄食模式的影响，另一个系统表现奎宁的影响。
